SFN appears to be as effective as modern antibiotics against the bacteria that cause peptic ulcers—and may provide a solution for treating antibiotic-resistant strains. 

Studies of human subjects have found that SFN significantly reduces the level of Helicobacter pylori bacteria in the lining of the stomach—which is the primary cause of gastritis and ulcers.


Yanaka A, Fahey JW, Fukumoto A, Nakayama M, Inoue S, Zhang S, Tauchi M, Suzuki H, Hyodo I, Yamamoto M. Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans. Cancer Prev Res (Phila). 2009 Apr;2(4):353-60. doi: 10.1158/1940-6207.CAPR-08-0192. PMID: 19349290.

Fahey JW, Haristoy X, Dolan PM, Kensler TW, Scholtus I, Stephenson KK, Talalay P, Lozniewski A. Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7610-5. doi: 10.1073/pnas.112203099. PMID: 12032331; PMCID: PMC124299.

Yanaka A. Role of Sulforaphane in Protection of Gastrointestinal Tract Against H. pylori and NSAID-Induced Oxidative Stress. Curr Pharm Des. 2017;23(27):4066-4075. doi: 10.2174/1381612823666170207103943. PMID: 28176666; PMCID: PMC5759180.