SFN has been robustly shown to increase brown adipose tissue (AKA “brown fat”)—which helps us lose weight. 

SFN has also been shown to increase leptin responsiveness, which decreases hunger. 

In mouse studies, SFN has significantly reduced obesity and weight gain.


Zhang HQ, Chen SY, Wang AS, Yao AJ, Fu JF, Zhao JS, Chen F, Zou ZQ, Zhang XH, Shan YJ, Bao YP. Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization. Mol Nutr Food Res. 2016 Oct;60(10):2185-2197. doi: 10.1002/mnfr.201500915. Epub 2016 Jun 16. PMID: 27218607; PMCID: PMC5111775.

Nagata N, Xu L, Kohno S, Ushida Y, Aoki Y, Umeda R, Fuke N, Zhuge F, Ni Y, Nagashimada M, Takahashi C, Suganuma H, Kaneko S, Ota T. Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice. Diabetes. 2017 May;66(5):1222-1236. doi: 10.2337/db16-0662. Epub 2017 Feb 16. PMID: 28209760.

Shawky NM, Segar L. Sulforaphane improves leptin responsiveness in high-fat high-sucrose diet-fed obese mice. Eur J Pharmacol. 2018 Sep 15;835:108-114. doi: 10.1016/j.ejphar.2018.07.050. Epub 2018 Jul 29. PMID: 30063917; PMCID: PMC6110095.